Search on: CCN INTERCELLULAR SIGNALING PROTEINS 
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Descriptor English:   CCN Intercellular Signaling Proteins 
Descriptor Spanish:   Proteínas CCN de Señalización Intercelular 
Descriptor Portuguese:   Proteínas de Sinalização Intercelular CCN 
Tree Number:   D12.644.276.200
D12.776.467.200
D12.776.860.300.200
D23.529.237
Definition English:   A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN. 
History Note English:   2009 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   53123 
Unique Identifier:   D055511 

Occurrence in VHL:
 

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